@article{1f9a03d54b8d4077b6b23c01508ef17c,
title = "Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan",
abstract = "Endometriosis, defined by the presence of viable extrauterine endometrial glands and stroma, can grow or bleed cyclically, and possesses characteristics including a destructive, invasive, and metastatic nature. Since endometriosis may result in pelvic inflammation, adhesion, chronic pain, and infertility, and can progress to biologically malignant tumors, it is a long-term major health issue in women of reproductive age. In this review, we analyze the Taiwan domestic research addressing associations between endometriosis and other diseases. Concerning malignant tumors, we identified four studies on the links between endometriosis and ovarian cancer, one on breast cancer, two on endometrial cancer, one on colorectal cancer, and one on other malignancies, as well as one on associations between endometriosis and irritable bowel syndrome, one on links with migraine headache, three on links with pelvic inflammatory diseases, four on links with infertility, four on links with obesity, four on links with chronic liver disease, four on links with rheumatoid arthritis, four on links with chronic renal disease, five on links with diabetes mellitus, and five on links with cardiovascular diseases (hypertension, hyperlipidemia, etc.). The data available to date support that women with endometriosis might be at risk of some chronic illnesses and certain malignancies, although we consider the evidence for some comorbidities to be of low quality, for example, the association between colon cancer and adenomyosis/endometriosis. We still believe that the risk of comorbidity might be higher in women with endometriosis than that we supposed before. More research is needed to determine whether women with endometriosis are really at risk of these comorbidities.",
keywords = "comorbidity, endometriosis, Taiwan",
author = "Teng, {Sen Wen} and Horng, {Huann Cheng} and Ho, {Chi Hong} and Yen, {Ming Shyen} and Chao, {Hsiang Tai} and Wang, {Peng Hui} and Chang, {Yen Hou} and Yi Chang and Chao, {Kuan Chong} and Chen, {Yi Jen} and Chuang, {Chi Mu} and Huang, {Yu Chen} and Jiang, {Ling Yu} and Li, {Hsin Yang} and Liu, {Chia Hao} and Sun, {Pi Lin} and Wen, {Kuo Chang} and Wu, {Hua Hsi} and Yu, {Hann Chin} and Ju, {Fong Yuan} and Tsai, {Chih Ping} and Chang, {Wen Hsun} and Hsu, {Yen Mei} and Huang, {Shu Yun} and Lee, {Na Rong} and Chen, {Chih Yao} and Chang, {Ting Chen} and Chang, {Wen Chun} and Chen, {Chii Hou} and Chen, {Ruey Jian} and Chow, {Song Nan} and Lien, {Yih Ron} and Sheu, {Bor Ching} and Torng, {Pao Ling} and Yen, {Men Luh} and Lee, {Wen Ling} and Wang, {Kuan Chin} and Chang, {Chih Long} and Chen, {Chih Ping} and Chen, {Jen Ruei} and Chen, {Tze Chien} and Huang, {Jian Pei} and Huang, {Ming Chao} and Wang, {Yeou Lih} and Chang, {Cheng Chang} and Liu, {Jah Yao} and Su, {Her Young} and Wang, {Yu Chi} and Yu, {Mu Hsien} and Chu, {Ching Chuang} and Huang, {Lee Wen} and Seow, {Kok Min} and Lai, {Tsung Hsuan} and Lee, {Fa Kung} and Chen, {Chii Hou} and Wei-Min Liu and Chiou, {Jyh Shin} and Huang, {Ben Shian} and Lu, {Yen Feng} and Hsiao, {Sheng Mou} and Sun, {Hsu Dong} and Wu, {Wen Yih} and Chen, {Kuo Hu} and Hung, {Jeng Hsiu} and Hung-Cheng Lai and Chiou-Chung Yuan and Hsieh, {Ching Hung} and Wang, {Chin Jung} and Chan, {Chia Hao} and Chang, {Shing Jyh} and Shih, {Chuan Chi} and Hung, {Man Jung} and Hsu, {Shih Tien} and Ke, {Yu Min} and Lu, {Chien Hsing} and Lou Sun and Chang, {Wei Chun} and Hung, {Yao Ching} and Lin, {Wu Chou} and Wang, {Po Hui} and Chen, {Tze Ho} and Li, {Yiu Tai} and Wu, {Meng Hsing} and Huang, {Kuo Feng} and Chuang, {Fei Chi} and Fu, {Hung Chun} and Kung, {Fu Tsai} and Huang, {Kuan Hui} and Chen, {San Nung} and Chiang, {An Jen} and Li, {Ju Yueh} and Lin, {Li Te} and Tsai, {Hsiao Wen} and Tsui, {Kuan Hao}",
note = "Funding Information: This work was supported by grants from the Ministry of Science and Technology , Executive Yuan ( MOST 103-2314-B-010-043-MY3 ), and Taipei Veterans General Hospital ( V102C-141 , V103C-112 , V104C-095 , V105C-096 , V102E4-003 , and V103E4-003 ). We also appreciate the Clinical Research Core Laboratory and the Medical Science & Technology Building of Taipei Veterans General Hospital for providing experimental space and facilities. Publisher Copyright: {\textcopyright} 2016",
year = "2016",
month = nov,
day = "1",
doi = "10.1016/j.jcma.2016.04.006",
language = "English",
volume = "79",
pages = "577--582",
journal = "Journal of the Chinese Medical Association",
issn = "1726-4901",
publisher = "Elsevier Taiwan LLC",
number = "11",
}