摘要
We aimed to examine the correlations between vitamin D deficiency, severity of dry eye symptoms and primary Sjögren’s syndrome (pSS) by performing a systematic review and meta-analysis. Online databases (PubMed, Cochrane Library, and Embase) were searched to identify controlled studies comparing (1) severity of dry eye symptoms between participants with and without vitamin D deficiency; and (2) serum vitamin D levels between patients with and without pSS. Eighteen studies were included. Overall, individuals with vitamin D deficiency had shorter tear breakup time (TBUT), lower Schirmer’s test scores and higher ocular surface disease index (OSDI) score than those without vitamin D deficiency. Additionally, serum vitamin D levels were found to be lower in pSS than controls. Our findings highlight the importance of vitamin D deficiency in the severity of dry eye symptoms and pSS.
原文 | 英語 |
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頁(從 - 到) | 386-388 |
頁數 | 3 |
期刊 | Journal of Nutritional Science and Vitaminology |
卷 | 66 |
發行號 | 4 |
DOIs | |
出版狀態 | 已發佈 - 2020 |
ASJC Scopus subject areas
- 醫藥(雜項)
- 營養與營養學