Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome in adults prognostic factors for outcomes

Meng Yu Wu, Chung Chi Huang, Tzu I. Wu, Chin Liang Wang, Pyng Jing Lin

研究成果: 雜誌貢獻文章同行評審

25 引文 斯高帕斯(Scopus)

摘要

Despite a therapeutic option for severe acute respiratory distress syndrome (ARDS), the survival benefit of venovenous extracorporeal membrane oxygenation (VV-ECMO) is still controversial in adults. This study was aimed at investigating the prognostic factors for ECMO-treated ARDS in adult patients. From 2012 to 2015, 49 patients (median age: 57 years) received VVECMO in our institution and were included in this retrospective study. The indication of VV-ECMO was a severe hypoxemia (PaO2/FiO2 ratio 35cmH2O and a FiO2 >0.8. To decrease the impact of pulmonary injuries associated with the high-pressure ventilation, the settings of MV on VV-ECMO were downgraded accorDing to our protocol. Outcomes of this study were death on VV-ECMO and death in hospital. Important demographic and clinical data during the treatment were collected for outcome analyses. All patients experienced significant improvements in arterial oxygenation onVV-ECMO.Twenty-four hours after initiation ofVV-ECMO, the median PaO2/FiO2 ratio increased from 58 to 172mmHg (P90 hours was the prognostic factor of death before hospital discharge (OR: 7, 95% CI: 1-29, P

原文英語
文章編號e2870
期刊Medicine (United States)
95
發行號8
DOIs
出版狀態已發佈 - 3月 4 2016

ASJC Scopus subject areas

  • 醫藥 (全部)

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