Triple screening of gynecology cancers using cervical DNA methylation

Epigenetic changes play an important role in cancer development. Our previous research on the epigenomics of cervical cancer using genome-wide approaches identified 14 candidate genes that were hypermethylated in cervical cancer tissues. Most of these genes are transcription factors and development-related genes that are common in the development of various cancers. Recent researchers demonstrated that gene mutations in cervical scrapings can reflect the status of endometrial and ovarian cancer tissues.