Treatment with a New Barbituric Acid Derivative Exerts Antiproliferative and Antimigratory Effects against Sorafenib Resistance in Hepatocellular Carcinoma

Chemical Compounds

• Antimigratory 100%
• Antiproliferative 55%
• Antitumor 10%
• Barbituric Acid 71%
• Carbon Atom 5%
• Cell Viability 11%
• Dose 8%
• Drug 17%
• Microarrays 12%
• Protein 4%
• Resistance 35%
• Sorafenib 87%

Medicine & Life Sciences

• Anti-Asthmatic Agents 5%
• Carbon Tetrachloride 4%
• Caspase 7 5%
• Cause of Death 3%
• Cell Movement 6%
• Cell Proliferation 2%
• Cell Survival 3%
• Drug Resistance 3%
• Epithelial-Mesenchymal Transition 4%
• Growth 4%
• Hepatocellular Carcinoma 45%
• Heterografts 3%
• Liver Cirrhosis 3%
• Liver Neoplasms 15%
• Microarray Analysis 4%
• Neoplasms 3%
• Pharmaceutical Preparations 1%
• Phosphorylation 2%
• Proteins 1%
• regorafenib 6%
• Sorafenib 68%
• Therapeutics 9%
• United States Food and Drug Administration 3%
• Vimentin 4%
• Western Blotting 2%
• Wound Healing 3%

Physics & Astronomy

• acids 49%
• cancer 52%
• carbon tetrachloride 3%
• causes 1%
• cells 5%
• death 3%
• dosage 3%
• drugs 8%
• fibrosis 4%
• inhibitors 3%
• liver 11%
• locomotion 3%
• mice 8%
• phosphorylation 3%
• proteins 2%
• therapy 2%
• viability 2%
• wound healing 3%