Transplantation of related histocompatible marrow and peripheral blood stem cells in a patient with severe combined immunodeficiency and disseminated BCG infection

Giun Yi Hung; Tzeon Jye Chiou; Ching Yuang Lin; Liang Tsai Hsiao; Po Min Chen; Betau Hwang

Transplantation of related histocompatible marrow and peripheral blood stem cells in a patient with severe combined immunodeficiency and disseminated BCG infection

Giun Yi Hung, Tzeon Jye Chiou, Ching Yuang Lin, Liang Tsai Hsiao, Po Min Chen, Betau Hwang

研究成果: 雜誌貢獻 › 文章 › 同行評審

摘要

We report the results of allogeneic bone marrow transplantation (BMT) in a 15-month-old boy with severe combined immunodeficiency (SCID) complicated by disseminated Bacillus Calmette-Guerin (BCG) infection. Slow immunological recovery after BMT is considered to be associated with prolonged BCG infection. After one booster dose of allogeneic peripheral blood stem cell transplantation (PBSCT), there was still little improvement in immune reconstitution. The patient finally expired because of failure to achieve a functioning immune system after BMT and septic shock.

原文	英語
頁（從 - 到）	72-75
頁數	4
期刊	Journal of the Chinese Medical Association
卷	66
發行號	1
出版狀態	已發佈 - 1月 2003
對外發佈	是

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abstract = "We report the results of allogeneic bone marrow transplantation (BMT) in a 15-month-old boy with severe combined immunodeficiency (SCID) complicated by disseminated Bacillus Calmette-Guerin (BCG) infection. Slow immunological recovery after BMT is considered to be associated with prolonged BCG infection. After one booster dose of allogeneic peripheral blood stem cell transplantation (PBSCT), there was still little improvement in immune reconstitution. The patient finally expired because of failure to achieve a functioning immune system after BMT and septic shock.",

keywords = "BCG infection, Bone marrow transplantation, Peripheral blood stem cell transplantation, Severe combined immunodeficiency",

author = "Hung, {Giun Yi} and Chiou, {Tzeon Jye} and Lin, {Ching Yuang} and Hsiao, {Liang Tsai} and Chen, {Po Min} and Betau Hwang",

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AU - Hsiao, Liang Tsai

AU - Chen, Po Min

AU - Hwang, Betau

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N2 - We report the results of allogeneic bone marrow transplantation (BMT) in a 15-month-old boy with severe combined immunodeficiency (SCID) complicated by disseminated Bacillus Calmette-Guerin (BCG) infection. Slow immunological recovery after BMT is considered to be associated with prolonged BCG infection. After one booster dose of allogeneic peripheral blood stem cell transplantation (PBSCT), there was still little improvement in immune reconstitution. The patient finally expired because of failure to achieve a functioning immune system after BMT and septic shock.

AB - We report the results of allogeneic bone marrow transplantation (BMT) in a 15-month-old boy with severe combined immunodeficiency (SCID) complicated by disseminated Bacillus Calmette-Guerin (BCG) infection. Slow immunological recovery after BMT is considered to be associated with prolonged BCG infection. After one booster dose of allogeneic peripheral blood stem cell transplantation (PBSCT), there was still little improvement in immune reconstitution. The patient finally expired because of failure to achieve a functioning immune system after BMT and septic shock.

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KW - Bone marrow transplantation

KW - Peripheral blood stem cell transplantation

KW - Severe combined immunodeficiency

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Transplantation of related histocompatible marrow and peripheral blood stem cells in a patient with severe combined immunodeficiency and disseminated BCG infection

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