@article{07f3ce3f85bf4e249e8aaff2d2e2e2c3,
title = "Toxicologic Concerns with Current Medical Nanoparticles",
abstract = "Nanotechnology is one of the scientific advances in technology. Nanoparticles (NPs) are small materials ranging from 1 to 100 nm. When the shape of the supplied nanoparticles changes, the physiological response of the cells can be very different. Several characteristics of NPs such as the composition, surface chemistry, surface charge, and shape are also important parameters affecting the toxicity of nanomaterials. This review covered specific topics that address the effects of NPs on nanomedicine. Furthermore, mechanisms of different types of nanomaterial-induced cytotoxicities were described. The distributions of different NPs in organs and their adverse effects were also emphasized. This review provides insight into the scientific community interested in nano(bio)technology, nanomedicine, and nanotoxicology. The content may also be of interest to a broad range of scientists.",
keywords = "cytotoxicity, ingestion, inhalation, medical applications, nanoparticles, nanotoxicity",
author = "Cheng, {Tsai Mu} and Chu, {Hsiu Yi} and Huang, {Haw Ming} and Li, {Zi Lin} and Chen, {Chiang Ying} and Shih, {Ya Jung} and Jacqueline Whang-Peng and Cheng, {R. Holland} and Mo, {Ju Ku} and Lin, {Hung Yun} and Kuan Wang",
note = "Funding Information: This work was supported in part by the Chair Professor Research Fund to K.W. and the TMU Research Center of Cancer Translational Medicine from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project, by the Ministry of Education (MOE) in Taiwan (DP2-107-20000), by a grant from the Ministry of Science and Technology, Taiwan (MOST109-2314-B-038-125 to H.-Y.L. and MOST 110-2314-B-038-031 to T.-M.C.), and by an integrated grant from the Ministry of Science and Technology, Taiwan (MOST110-2314-B-038-114 to J.W.-P.; MOST110-2314-B-038-119 to K.W. and MOST110-2314-B-038-115 to H.-Y.L.), and by NIH TR002866, CA225266, EB021230, U19 Canter for STI Vaccine developments, as well as NIFA CADMCB-7399-H and Astrid Pharma A18-1773 USA (to R.H.C.). Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2022",
month = jul,
day = "8",
doi = "10.3390/ijms23147597",
language = "English",
volume = "23",
journal = "International journal of molecular sciences",
issn = "1661-6596",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "14",
}