TY - JOUR
T1 - The ultrasensitive silver "protein" stain also detects nanograms of nucleic acids
AU - Somerville, Laura L.
AU - Wang, Kuan
PY - 1981/9/16
Y1 - 1981/9/16
N2 - The ultrasensitive silver staining procedure developed for proteins also stains nanogram quantities of RNA and DNA in polyacrylamide gels. A gradient polyacrylamide gel system is described which separates proteins from 104 to 106 Mr, RNA from 5S to 23S and DNA from 0.4 to 21 Kb. The sensitivity of nucleic acid silver staining in this gel system considerably exceeds that of commonly used DNA and RNA dye-binding stains.
AB - The ultrasensitive silver staining procedure developed for proteins also stains nanogram quantities of RNA and DNA in polyacrylamide gels. A gradient polyacrylamide gel system is described which separates proteins from 104 to 106 Mr, RNA from 5S to 23S and DNA from 0.4 to 21 Kb. The sensitivity of nucleic acid silver staining in this gel system considerably exceeds that of commonly used DNA and RNA dye-binding stains.
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U2 - 10.1016/0006-291X(81)91487-X
DO - 10.1016/0006-291X(81)91487-X
M3 - Article
C2 - 6171285
AN - SCOPUS:0019857184
SN - 0006-291X
VL - 102
SP - 53
EP - 58
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 1
ER -