摘要
Background: DNA mimic proteins prevent DNA-binding proteins from binding to DNA.
Results: T4 phage DNA mimic protein Arn disrupts H-NS·DNA binding and neutralizes the gene-silencing effect of H-NS.
Conclusion: Arn participates in viral anti-host defense system by its DNA mimicking properties.
Significance: This anti-H-NS function of Arn represents a novel battle mechanism between phage and bacteria.
Results: T4 phage DNA mimic protein Arn disrupts H-NS·DNA binding and neutralizes the gene-silencing effect of H-NS.
Conclusion: Arn participates in viral anti-host defense system by its DNA mimicking properties.
Significance: This anti-H-NS function of Arn represents a novel battle mechanism between phage and bacteria.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 27046-27054 |
| 頁數 | 9 |
| 期刊 | Journal of Biological Chemistry |
| 卷 | 289 |
| 發行號 | 39 |
| DOIs | |
| 出版狀態 | 已發佈 - 9月 26 2014 |
ASJC Scopus subject areas
- 生物化學
- 分子生物學
- 細胞生物學
指紋
深入研究「The T4 phage DNA mimic protein arn inhibits the DNA binding activity of the bacterial histone-like protein H-NS」主題。共同形成了獨特的指紋。資料集
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3WX4 : CRYSTAL STRUCTURE of T4 PHAGE ARN PROTEIN
Ho, C. (Contributor), Wang, H. (Contributor), Ko, T. (Contributor) & Wang, A. H. (Contributor), RCSB-PDB, 2014
DOI: 10.2210/pdb3wx4/pdb, https://www.rcsb.org/structure/3WX4
資料集: Dataset