摘要
The prototype Th2 cytokine IL-4, and its competitive antagonist IL-4δ2, may be important determinants of outcome in human tuberculosis (TB). However, there are no data on how gene expression of these cytokines is regulated. To evaluate this the stability of IL-4 and IL-4δ2 mRNA after the addition of actinomycin-D, was evaluated in whole blood from subjects with pulmonary TB and uninfected healthy volunteers. The Th2/Th1 (IL-4/IFN-γ) mRNA ratio in unstimulated cells in whole blood was significantly greater in TB subjects than in controls (p
原文 | 英語 |
---|---|
頁(從 - 到) | 237-241 |
頁數 | 5 |
期刊 | Tuberculosis |
卷 | 87 |
發行號 | 3 |
DOIs | |
出版狀態 | 已發佈 - 5月 2007 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 應用微生物與生物技術
- 微生物學
- 免疫學和過敏
- 傳染性疾病
- 獸醫 (全部)