The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma

Wen Wei Sung; Huei Lee

doi:10.4161/onci.25854

The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma

Wen Wei Sung, Huei Lee

癌症生物學與藥物研發博士學位學程

研究成果: 雜誌貢獻 › 文章 › 同行評審

15 引文斯高帕斯（Scopus）

摘要

The secretion of interleukin-10 by both malignant and immune cells promotes the progression of lung tumors, hence negatively impacting on patient prognosis. As interleukin-10 mediates oncogenic effects through the PI3K/AKT signaling pathway, PI3K/AKT inhibitors might sensitize cancer cells to chemotherapy, thus favoring tumor regression and improving disease outcome.

原文	英語
文章編號	e25854
期刊	OncoImmunology
卷	2
發行號	9
DOIs	https://doi.org/10.4161/onci.25854
出版狀態	已發佈 - 2013

ASJC Scopus subject areas

免疫學和過敏
腫瘤科
免疫學

UN SDG

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10.4161/onci.25854

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abstract = "The secretion of interleukin-10 by both malignant and immune cells promotes the progression of lung tumors, hence negatively impacting on patient prognosis. As interleukin-10 mediates oncogenic effects through the PI3K/AKT signaling pathway, PI3K/AKT inhibitors might sensitize cancer cells to chemotherapy, thus favoring tumor regression and improving disease outcome.",

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KW - IL-10

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KW - Lung cancer

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The role of interleukin-10 in the progression of human papillomavirus-associated lung carcinoma

摘要

ASJC Scopus subject areas

UN SDG

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