The immunomodulatory effects of lactic acid bacteria for improving immune functions and benefits

Yueh Ting Tsai, Po Ching Cheng, Tzu Ming Pan

研究成果: 雜誌貢獻文章同行評審

168 引文 斯高帕斯(Scopus)


Probiotics have a number of beneficial health effects in humans and animals, such as reducing lactose intolerance symptoms and enhancing the bioavailability of nutrients. Probiotics help regulate intestinal microflora and immunomodulatory properties. Probiotics also decrease the prevalence of allergies in susceptible individuals, inhibit the inflammatory responses in the gut, and have antagonistic effects against intestinal and food-borne pathogens. Bacteria typically colonize the intestinal tract first and then reinforce the host defense systems by inducing generalized mucosal immune responses, including modulation of DC/NK interaction, a balanced T-helper cell response, self-limited inflammatory response, and the secretion of polymeric IgA. A lot of reports showed that lactic acid bacteria (LAB) as Lactobacillus and Bifidobacterium and their fermented products are effective at enhancing innate and adaptive immunity, prevent gastric mucosal lesion development, alleviate allergies, and put up defense against intestinal pathogen infection. In this review paper, we compared the influence of immunomodulatory effects on the function and efficacy of lactobacillus products with different strains. We also discuss the beneficial effects of several LAB strain and its derivative products for human immunity and related diseases.

頁(從 - 到)853-862
期刊Applied Microbiology and Biotechnology
出版狀態已發佈 - 11月 2012

ASJC Scopus subject areas

  • 生物技術
  • 應用微生物與生物技術


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