TY - BOOK
T1 - The Bioimaging Applications of Mesoporous Silica Nanoparticles
T2 - Enzymes
AU - Pratiwi, F.W.
AU - Kuo, C.W.
AU - Wu, S.-H.
AU - Chen, Y.-P.
AU - Mou, C.Y.
AU - Chen, P.
A2 - F., Tamanoi
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - The unique features of Mesoporous Silica Nanoparticles (MSNs) provide a suitable platform to carry fluorescence dyes for various bioimaging applications. Several strategies have been developed to conjugate a variety of dyes either in the pores or on the surfaces of MSNs to form the fluorescence MSNs (FMSNs). In this chapter, we will discuss recent research progress and future development of FMSNs for living system imaging. We will first describe different strategies for the fabrications of FMSNs. Then, we will discuss the recent developments of cellular and intracellular imaging including self-probe for the interactions of FMSNs with the cells, receptor and organelle labeling, sensing and tracking of biological system, and monitoring the drug delivery and release processes. Moreover, we will include the applications of FMSNs as contrast agents for in vivo imaging. Finally, we will conclude and highlight the challenges and opportunities for MSNs in medical applications.
AB - The unique features of Mesoporous Silica Nanoparticles (MSNs) provide a suitable platform to carry fluorescence dyes for various bioimaging applications. Several strategies have been developed to conjugate a variety of dyes either in the pores or on the surfaces of MSNs to form the fluorescence MSNs (FMSNs). In this chapter, we will discuss recent research progress and future development of FMSNs for living system imaging. We will first describe different strategies for the fabrications of FMSNs. Then, we will discuss the recent developments of cellular and intracellular imaging including self-probe for the interactions of FMSNs with the cells, receptor and organelle labeling, sensing and tracking of biological system, and monitoring the drug delivery and release processes. Moreover, we will include the applications of FMSNs as contrast agents for in vivo imaging. Finally, we will conclude and highlight the challenges and opportunities for MSNs in medical applications.
KW - Bioimaging
KW - Mesoporous silica nanoparticles
KW - Nanomedicine
KW - Surface modification
KW - Targeted delivery
KW - Theranostics
UR - http://www.scopus.com/inward/record.url?scp=85052997125&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85052997125&partnerID=8YFLogxK
U2 - 10.1016/bs.enz.2018.07.006
DO - 10.1016/bs.enz.2018.07.006
M3 - Book
C2 - 30244805
SN - 9780128151129
VL - 43
T3 - Enzymes
BT - The Bioimaging Applications of Mesoporous Silica Nanoparticles
PB - International Academic Press
ER -