@article{14afa57ba2eb43628b4a5f3a08fcd0f1,
title = "The anticancer properties and apoptosis-inducing mechanisms of cinnamaldehyde and the herbal prescription Huang-Lian-Jie-Du-Tang (Hu{\'a}ng Li{\'a}n Ji{\v e} D{\'u} Tang) in human hepatoma cells",
abstract = "Hepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang Lian Jie Du Tang (Hu{\'a}ng Li{\'a}n Ji{\v e} D{\'u} Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed.",
keywords = "Anticancer, Apoptosis, Cinnamaldehyde, Hepatoma, Huang-Lian-Jie-Du-Tang",
author = "Lin, {Liang Tzung} and Wu, {Shu Jing} and Lin, {Chun Ching}",
note = "Funding Information: LTL was supported by funding from Taipei Medical University (TMU101-AE3-Y19). CCL was supported by a research grant from the Committee on Chinese Medicine and Pharmacy, Department of Health, Executive Yuan of Taiwan (CCMP 95-RD-212). SJW received support from the National Science Council of Taiwan (NSC96-2313-B-041-004).",
year = "2013",
doi = "10.4103/2225-4110.119732",
language = "English",
volume = "3",
pages = "227--233",
journal = "Journal of Traditional and Complementary Medicine",
issn = "2225-4110",
publisher = "Elsevier BV",
number = "4",
}