Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-Like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells

Medicine and Dentistry

• Malignant Neoplasm 100%
• Non Small Cell Lung Cancer 100%
• Carcinoma Cell 100%
• Sterol Regulatory Element Binding Protein 1 100%
• Cancer Stem Cell 18%
• Lung Cancer 18%
• Short Hairpin RNA 18%
• microRNA 18%
• Sterol Regulatory Element Binding Protein 18%
• Cisplatin 18%
• Mortality Rate 9%
• Fatty Acid 9%
• Diagnosis 9%
• Neoplasm 9%
• down Regulation 9%
• Treatment Response 9%
• Western Blot 9%
• Cell Viability 9%
• Protein Function 9%
• Real-Time Polymerase Chain Reaction 9%
• Biological Functions 9%
• Cancer Types 9%
• In Silico 9%
• Gene Expression Omnibus 9%
• Lung Non-Small Cell Carcinoma Cell Line 9%
• Phospholipid 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Non Small Cell Lung Cancer 100%
• Sterol Regulatory Element Binding Protein 1 100%
• microRNA 18%
• Lung Cancer 18%
• Short Hairpin RNA 18%
• Cisplatin 18%
• Sterol Regulatory Element Binding Protein 18%
• Mortality Rate 9%
• Fatty Acid 9%
• Western Blot 9%
• Cell Viability 9%
• Neoplasm 9%
• Phospholipid 9%

Biochemistry, Genetics and Molecular Biology

• Sterol Regulatory Element Binding Protein 1 100%
• MicroRNA 18%
• Cisplatin 18%
• Sterol Regulatory Element-Binding Protein 18%
• Cancer Stem Cell 18%
• Small Hairpin RNA 18%
• Gene Expression 9%
• Mortality Rate 9%
• Computer Model 9%
• down Regulation 9%
• Epigenetics 9%
• Anticancer 9%
• Real-Time Polymerase Chain Reaction 9%
• Protein Function 9%
• Phospholipid 9%
• Cell Viability 9%
• Biological Functions 9%
• Reprogramming 9%
• Western Blot 9%