Synthesis and Integration of Virus-specific DNA in Cells Infected by RNA Tumor Viruses

H. E. Varmus, P. R. Shank, Hsing-Jien Kung

研究成果: 書貢獻/報告類型章節

摘要

After infection of either permissive or nonpermissive cells by RNA tumor viruses, viral genetic information appears to persist indefinitely in the form of virus-specific, double-stranded DNA integrated covalently into the host chromosome (Varmus et al., 1975; Weinberg, 1977). In this report, we summarize our progress in deciphering the sequence of molecular events that culminates in the integration of viral DNA into the DNA of avian cells infected by avian sarcoma virus (ASV), and we offer our current view of the mechanisms involved.
原文英語
主出版物標題Integration and Excision of DNA Molecules
發行者Springer Berlin Heidelberg
頁面95-100
ISBN(電子)978-3-642-81203-3
ISBN(列印)978-3-642-81205-7
出版狀態已發佈 - 1978
對外發佈

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