Synthesis and Biological Evaluation of Some 1‐Substituted 3‐(2‐Perimidyl)ureas

Kang‐Chien ‐C Liu, Hsu‐Shan ‐S Huang

研究成果: 雜誌貢獻文章同行評審

3 引文 斯高帕斯(Scopus)

摘要

Some representative 1‐substituted 3‐(2‐perimidyl)ureas were prepared by treatment of 2‐aminoperimidine hydrobromide with the corresponding isocyanates in the presence of triethylamine. A preliminary biological evaluation for their antibacterial and cytotoxic properties revealed that only those compounds which contain a chlorinated substituent at N‐1 exhibited some notable effect.

原文英語
頁(從 - 到)425-426
頁數2
期刊Archiv der Pharmazie
321
發行號7
DOIs
出版狀態已發佈 - 1988
對外發佈

ASJC Scopus subject areas

  • 藥物發現
  • 藥學科學

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