@article{41f2968cdac746b1b0f2b227ae9fb40e,
title = "Structure-activity and crystallographic analysis of benzophenone derivatives - The potential anticancer agents",
abstract = "Compounds 1-5, structurally related to combretastatin A-4 showed excellent cytotoxic activities against a panel of human cancer cell lines including multi-drug resistant cell lines. The X-ray three-dimensional structural analysis shows that proton donor in B ring may be required for cytotoxic activity, with intermolecular hydrogen bonding playing an important role.",
author = "Hsieh, {Hsing Pang} and Liou, {Jing Ping} and Lin, {Ying Ting} and Neeraj Mahindroo and Chang, {Jang Yang} and Yang, {Yung Ning} and Chern, {Shuenn Shing} and Tan, {Uan Kang} and Chang, {Chun Wei} and Chen, {Tung Wei} and Lin, {Chi Hung} and Chang, {Ying Ying} and Wang, {Chiung Chiu}",
note = "Funding Information: This work was financially supported by National Health Research Institutes, Taiwan, Republic of China. The authors are grateful to Ms. Edith Hsiao-Wen Chu and Ms. Shiau-Fen Jung for their administrative supports. ",
year = "2003",
month = jan,
day = "6",
doi = "10.1016/S0960-894X(02)00850-8",
language = "English",
volume = "13",
pages = "101--105",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Ltd",
number = "1",
}
