Structural Consequences of a Carcinogenic Alkylation Lesion on DNA: Effect of O⁶-Ethylguanine on the Molecular Structure of D(Cgc[e⁶G]Aattcgcg)-Netropsin Complex

Biochemistry, Genetics and Molecular Biology

• Chemical Structure 100%
• Alkylation 100%
• Netropsin 100%
• Crystal 40%
• Hydrogen Bond 30%
• Crystal Structure 20%
• Drug Binding 20%
• Thymine 20%
• Point Mutation 10%
• Transcription 10%
• DNA Damage 10%
• X-Ray Crystallography 10%
• Biochemistry 10%
• R-Factor 10%
• Base Pairing 10%

Neuroscience

• Netropsin 100%
• Alkylation 100%
• Drug Binding 20%
• Thymine 20%
• Hoechst 33342 10%
• Nitrosourea 10%
• DNA Damage 10%
• Point Mutation 10%
• Double Stranded DNA 10%
• R Factor 10%
• Base Pairing 10%
• Alkylating Antineoplastic Agent 10%
• Carboxamide 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Congocidine 100%
• Base 100%
• Hydrogen Bond 25%
• Thymine 16%
• Hoe 33342 8%
• Double Stranded DNA 8%
• R-Factor 8%
• Alkylating Agent 8%
• 4 [5 (4 Methyl 1 piperazinyl)[2,5' Bi 1h Benzimidazol] 2' Yl]phenol 8%
• Carboxamide 8%
• Nitrosourea 8%
• Nitrogen 8%