Stevens-Johnson syndrome after treatment with STI571: A case report

Liang Tsai Hsiao; Hung Ming Chung; Jen Tsun Lin; Tzeon Jye Chiou; Jin Hwang Liu; Frank S. Fan; Wei Shu Wang; Chueh Chuan Yen; Po Min Chen

doi:10.1046/j.1365-2141.2002.03499.x

Stevens-Johnson syndrome after treatment with STI571: A case report

Liang Tsai Hsiao, Hung Ming Chung, Jen Tsun Lin, Tzeon Jye Chiou, Jin Hwang Liu, Frank S. Fan, Wei Shu Wang, Chueh Chuan Yen, Po Min Chen

研究成果: 雜誌貢獻 › 文章 › 同行評審

105 引文斯高帕斯（Scopus）

摘要

Between seven and 21% of patients treated with the specific tyrosine kinase inhibitor STI571 have been reported to develop mild-to-moderate severity of adverse cutaneous reactions. We report a patient in the blast crisis phase of chronic myeloid leukaemia who developed a life- threatening cutaneous reaction, Stevens-Johnson syndrome, following 1 week of STI571 therapy. This report may serve to remind the clinician about the possible severe cutaneous side-effects of STI571 before instituting more extensive clinical application of this agent in the future.

原文	英語
頁（從 - 到）	620-622
頁數	3
期刊	British Journal of Haematology
卷	117
發行號	3
DOIs	https://doi.org/10.1046/j.1365-2141.2002.03499.x
出版狀態	已發佈 - 2002
對外發佈	是

ASJC Scopus subject areas

血液學

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10.1046/j.1365-2141.2002.03499.x

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title = "Stevens-Johnson syndrome after treatment with STI571: A case report",

abstract = "Between seven and 21% of patients treated with the specific tyrosine kinase inhibitor STI571 have been reported to develop mild-to-moderate severity of adverse cutaneous reactions. We report a patient in the blast crisis phase of chronic myeloid leukaemia who developed a life- threatening cutaneous reaction, Stevens-Johnson syndrome, following 1 week of STI571 therapy. This report may serve to remind the clinician about the possible severe cutaneous side-effects of STI571 before instituting more extensive clinical application of this agent in the future.",

keywords = "Chronic myeloid leukaemia, Skin, Stevens-Johnson syndrome, STI571, Tyrosine kinase inhibitor",

author = "Hsiao, {Liang Tsai} and Chung, {Hung Ming} and Lin, {Jen Tsun} and Chiou, {Tzeon Jye} and Liu, {Jin Hwang} and Fan, {Frank S.} and Wang, {Wei Shu} and Yen, {Chueh Chuan} and Chen, {Po Min}",

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AU - Fan, Frank S.

AU - Wang, Wei Shu

AU - Yen, Chueh Chuan

AU - Chen, Po Min

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AB - Between seven and 21% of patients treated with the specific tyrosine kinase inhibitor STI571 have been reported to develop mild-to-moderate severity of adverse cutaneous reactions. We report a patient in the blast crisis phase of chronic myeloid leukaemia who developed a life- threatening cutaneous reaction, Stevens-Johnson syndrome, following 1 week of STI571 therapy. This report may serve to remind the clinician about the possible severe cutaneous side-effects of STI571 before instituting more extensive clinical application of this agent in the future.

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KW - Skin

KW - Stevens-Johnson syndrome

KW - STI571

KW - Tyrosine kinase inhibitor

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Stevens-Johnson syndrome after treatment with STI571: A case report

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