Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

Yu-Ching Wen; Wei Yu Chen; Wei Jiunn Lee; Shun Fa Yang; Liang Ming Lee; Ming Hsien Chien

doi:10.1016/j.cca.2014.01.036

Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

研究成果: 雜誌貢獻 › 文章 › 同行評審

摘要

Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p

原文	英語
頁（從 - 到）	169-173
頁數	5
期刊	Clinica Chimica Acta
卷	431
DOIs	https://doi.org/10.1016/j.cca.2014.01.036
出版狀態	已發佈 - 4月 20 2014

UN SDG

此研究成果有助於以下永續發展目標

SDG 3 良好的健康和福祉

ASJC Scopus subject areas

生物化學
臨床生物化學
生物化學（醫學）

存取文件

10.1016/j.cca.2014.01.036

其它文件與鏈接

Link to publication in Scopus

引用此

@article{0876eff4f2014bacb86d084d7f9f8c31,

title = "Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy",

abstract = "Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p",

keywords = "Prostate cancer, Radical prostatectomy, Recurrence, Snail, Stage T2",

author = "Yu-Ching Wen and Chen, \{Wei Yu\} and Lee, \{Wei Jiunn\} and Yang, \{Shun Fa\} and Lee, \{Liang Ming\} and Chien, \{Ming Hsien\}",

note = "Funding Information: This study was supported by grant numbers TMU101-AE3-Y22 , DOH-TD-B-111-003 , and TMU-CECR , and DOH102-TD-C-111-008 from the Taipei Medical University .",

year = "2014",

month = apr,

day = "20",

doi = "10.1016/j.cca.2014.01.036",

language = "English",

volume = "431",

pages = "169--173",

journal = "Clinica Chimica Acta",

issn = "0009-8981",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

AU - Wen, Yu-Ching

AU - Chen, Wei Yu

AU - Lee, Wei Jiunn

AU - Yang, Shun Fa

AU - Lee, Liang Ming

AU - Chien, Ming Hsien

N1 - Funding Information: This study was supported by grant numbers TMU101-AE3-Y22 , DOH-TD-B-111-003 , and TMU-CECR , and DOH102-TD-C-111-008 from the Taipei Medical University .

PY - 2014/4/20

Y1 - 2014/4/20

N2 - Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p

AB - Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p

KW - Prostate cancer

KW - Radical prostatectomy

KW - Recurrence

KW - Snail

KW - Stage T2

UR - https://www.scopus.com/pages/publications/84896726066

UR - https://www.scopus.com/pages/publications/84896726066#tab=citedBy

U2 - 10.1016/j.cca.2014.01.036

DO - 10.1016/j.cca.2014.01.036

M3 - Article

C2 - 24513541

AN - SCOPUS:84896726066

SN - 0009-8981

VL - 431

SP - 169

EP - 173

JO - Clinica Chimica Acta

JF - Clinica Chimica Acta

ER -

Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

摘要

UN SDG

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

引用此