@article{f89c65d949864e98a9cb72ddb4aa7bfc,
title = "Secondary metabolites from the stems of Engelhardia roxburghiana and their antitubercular activities",
abstract = "Bioassay-guided fractionation of stems of Engelhardia roxburghiana led to isolation of: four diarylheptanoids, engelheptanoxides A-D (1-4); two cyclic diarylheptanoids, engelhardiols A (5) and B (6); one naphthoquinone dimer, engelharquinonol (7); and one 1-tetralone, (4S)-4,6-dihydroxy-1-tetralone (8), along with 24 known compounds (9-32). The structures of 1-8 were by spectroscopic analysis. Compounds 5, 6, 13, 22, and 23 showed antitubercular activity against Mycobacterium tuberculosis H37Rv with MIC values of 72.7, 62.1, 9.1, 15.3, and 70.1 μM, respectively.",
keywords = "Antitubercular activity, Diarylheptanoid, Engelhardia roxburghiana, Juglandaceae, Naphthoquinone dimer, Stem, Tetralone",
author = "Wu, {Ho Chen} and Cheng, {Ming Jen} and Peng, {Chien Fang} and Yang, {Shyh Chyun} and Chang, {Hsun Shuo} and Lin, {Chu Hung} and Wang, {Chyi Jia} and Chen, {Ih Sheng}",
note = "Funding Information: This research was kindly supported by the National Science Council (NSC, Taiwan) and the Kaohsiung Medical University Research Foundation (KMUER013). ",
year = "2012",
month = oct,
doi = "10.1016/j.phytochem.2012.06.014",
language = "English",
volume = "82",
pages = "118--127",
journal = "Phytochemistry",
issn = "0031-9422",
publisher = "Elsevier Limited",
}
