摘要

In the present study, we indicated that the detection of specific subtypes of circulating tumor microemboli (CTM) in post-operative patients could help predict cancer recurrence. By using conventional strategies for detection of non-small-cell lung cancer (NSCLC) circulating tumor cells, is significantly limited due to inherently heterogeneous and dynamic expression of EpCAM, and degradation of cytokeratins during epithelial-tomesenchymal transition. These lead to non-negligible false negative detection of “uncapturable and invisible” single CTCs. To solve the problem, we investigated the clinical significance of CTM subtypes, including single CTCs, multi-CTCs cluster, and WBC-CTCs cluster on SACA chip for studying cancer metastasis and recurrence in patients with lung adenocarcinoma.

原文英語
主出版物標題MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
發行者Chemical and Biological Microsystems Society
頁面1141-1142
頁數2
ISBN(電子)9781733419017
出版狀態已發佈 - 2020
事件24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
持續時間: 10月 4 202010月 9 2020

出版系列

名字MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

會議

會議24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
城市Virtual, Online
期間10/4/2010/9/20

ASJC Scopus subject areas

  • 化學工程(雜項)
  • 生物工程
  • 化學 (全部)
  • 控制與系統工程

指紋

深入研究「Saca chip enabled circulating tumor cell clusters phenotyping for cancer immunotherapy response monitoring」主題。共同形成了獨特的指紋。

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