Rutaecarpine, an alkaloid from evodia rutaecarpa, can prevent platelet activation in humans and reduce microvascular thrombosis in mice: crucial role of the pi3k/akt/gsk3β signal axis through a cyclic nucleotides/vasp—independent mechanism

Chun Jen Huang, Wei Chieh Huang, Wei Ting Lin, Lan Hsin Shu, Joen Rong Sheu, Oanh Thi Tran, Chih Wei Hsia, Thanasekaran Jayakumar, Periyakali Saravana Bhavan, Cheng Ying Hsieh, Chao Chien Chang

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science