Risk of stroke among patients with cerebral palsy: a population-based cohort study

Chin Wen Wu, Shih-Wei Huang, Jia-Wei Lin, Tsan-Hon Liou, Lin Chuan Chou, Hui Wen Lin

研究成果: 雜誌貢獻文章同行評審

16 引文 斯高帕斯(Scopus)


Aim: The aim of the study was to investigate the risk of stroke in patients with cerebral palsy (CP), based on nationwide data in Taiwan. Method: This prospective cohort study was comprised of patients recorded on the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005) who had a diagnosis of CP (n=1975) in records between 1 January 2004 and 31 December 2007. A comparison group (1:5) drawn from the same database was matched for age and sex (n=9875). Each patient was tracked by data until the development of stroke or the end of 2008. Cox proportional-hazards regression analysis was used to evaluate the hazard ratios after adjusting for potential confounding factors. Results: Patients with CP were more likely to suffer stroke than the comparison population, after adjusting for potential confounding factors (adjusted hazard ratio: 2.17; 95% confidence interval [CI]: 1.74–2.69). The hazard ratio of stroke was 4.78 (95% CI: 3.18–7.17) and 1.57 (95% CI: 1.20–2.05) for patients with CP aged 50 years and under, and over 50 years respectively. Interpretation: Cerebral palsy is a risk factor or marker for stroke that is independent of traditional stroke risk factors. Further research in this area is warranted.
頁(從 - 到)52-56
期刊Developmental Medicine and Child Neurology
出版狀態已發佈 - 1月 1 2017

ASJC Scopus subject areas

  • 兒科、圍產兒和兒童健康
  • 發展神經科學
  • 神經病學(臨床)


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