@article{d9d5990200ad44cb890a4ac9769726b6,
title = "Risk of skin cancer among patients with chronic kidney disease treated with ultraviolet b phototherapy for uraemic pruritus: A nationwide cohort study",
abstract = "The safety of ultraviolet B (UVB) phototherapy with respect to cutaneous carcinogenesis has not been established for patients with chronic kidney disease. To investigate this issue, a nationwide cohort study of 10,805 patients with advanced chronic kidney disease was conducted using data from the National Health Insurance of Taiwan, the Taiwan Cancer Registry, and the national death registry. After a median follow-up of 75 months, 16 of 2,161 patients in the UVB group and 63 of 8,644 patients in the non-UVB group developed skin cancers. Compared with the non-UVB group, patients in the UVB group did not show an increased risk of skin cancer (hazard ratio 1.066; 95\% confidence interval 0.584–1.944), non-melanoma skin cancer (hazard ratio 1.067; 95\% confidence interval 0.571–1.996), or cutaneous melanoma (hazard ratio 1.009; 95\% confidence interval 0.115–8.879). In addition, patients who received more UVB phototherapy did not show an increased risk of skin cancer. UVB phototherapy appears to be a safe treatment for uraemic pruritus in patients with chronic kidney disease.",
keywords = "Chronic kidney disease, Skin cancer, Uraemic pruritus, UVB phototherapy",
author = "Ko, \{Mei Ju\} and Huang, \{Jenq Wen\} and Wu, \{Hon Yen\} and Tsai, \{Wan Chuan\} and Hsu, \{Le Yin\} and Tsai, \{Ping Hsiu\} and Chien, \{Kuo Liong\} and Hung, \{Kuan Yu\}",
note = "Funding Information: This study was supported by research grants to Dr HonYen Wu from the National Health Research Institutes, Taiwan (NHRIEX10810510PC, NHRIEX11011026PI) and the Far Eastern Memorial Hospital, New Taipei City, Taiwan (FEMHEX108-10510PC, FEMH2020C025), as well as by research grants to Dr MeiJu Ko from the Department of Health, Taipei City Government (1070162005, 1080162007) and the Taipei City Hospital, Taipei City, Taiwan (TPCH10917, TPCH10821). The funders had no role in study design, data collection, data analysis, manuscript preparation or publication decisions. Publisher Copyright: {\textcopyright} 2021, Medical Journals/Acta D-V. All rights reserved.",
year = "2021",
doi = "10.2340/00015555-3758",
language = "English",
volume = "101",
pages = "1--6",
journal = "Acta Dermato-Venereologica",
issn = "0001-5555",
publisher = "Medical Journals Sweden AB",
number = "2",
}
