Risk and protective factors for suicide mortality among patients with alcohol dependence

Galen Chin Lun Hung, Chia Tzu Cheng, Jia Rong Jhong, Shang Ying Tsai, Chiao Chicy Chen, Chian Jue Kuo

研究成果: 雜誌貢獻文章同行評審

16 引文 斯高帕斯(Scopus)


Objective: People with alcohol dependence suffer from poor health outcomes, including excessive suicide mortality. This study estimated the suicide rate and explored the risk and protective factors for suicide in a large-scale Asian population. Method: We enrolled patients with alcohol dependence (ICD-9 code 303) consecutively admitted to a psychiatric center in northern Taiwan from January 1, 1985, through December 31, 2008 (N = 2,793). Using patient linkage to the national mortality database (1985-2008), we determined that 960 patients died during the study period. Of those deaths, 65 patients died of suicide. On the basis of risk-set sampling for the selection of controls, we conducted a nested case-control study and collected the information by means of a standardized chart review process. We estimated the standardized mortality ratio (SMR) for suicide mortality. Conditional logistic regression was employed for exploring the risk and protective factors for suicide. Results: The study subjects had excessive suicide and all-cause deaths, with SMRs of 21.2 and 12.7, respectively. We pinpointed auditory hallucination (adjusted risk ratio [aRR] = 1.80, P = .04) and attempted suicide (aRR = 7.52, P = .001) as the risk factors associated with suicide. In contrast, protective factors included financial independence (aRR = 0.11, P = .005) and being married (aRR = 0.16, P = .02). Intriguingly, those with physical illnesses had a lower risk of suicide (aRR = 0.15, P = .01). Conclusions: Compared with the general population, those with alcohol dependence faced excessive suicide mortality. For a comprehensive approach to suicide prevention, recognizing and improving the protective factors could have equal importance in mitigating the risk of suicide.

頁(從 - 到)1687-1693
期刊Journal of Clinical Psychiatry
出版狀態已發佈 - 12月 2015

ASJC Scopus subject areas

  • 精神病學和心理健康


深入研究「Risk and protective factors for suicide mortality among patients with alcohol dependence」主題。共同形成了獨特的指紋。