Retinoic acid blocks pro-inflammatory cytokine-induced matrix metalloproteinase production by down-regulating JNK-AP-1 signaling in human chondrocytes

Pharmacology, Toxicology and Pharmaceutical Science

• Cytokine 100%
• Retinoic Acid 100%
• Matrix Metalloproteinase 100%
• Osteoarthritis 83%
• Tumor Necrosis Factor 50%
• Interleukin 1 50%
• Phosphotransferase 33%
• Enzyme-Linked Immunosorbent Assay 16%
• Western Blot 16%
• Nuclear Factor 16%
• Mitogen Activated Protein Kinase 16%
• Transcription Factor AP 1 16%
• RNA Directed DNA Polymerase 16%
• Interstitial Collagenase 16%
• Collagenase 3 16%
• Immunopathogenesis 16%
• Retinoid Derivative 16%
• Phosphotransferase Activator 16%
• Antioxidant 16%
• Protein Kinases 16%
• Transcription Factors 16%
• Retinol 16%
• Electrophoretic Mobility Shift Assay 16%

Immunology and Microbiology

• Proinflammatory Cytokine 100%
• Chondrocyte 100%
• Osteoarthritis 83%
• Tumor Necrosis Factor Alpha 50%
• Interleukin 1 50%
• DNA Binding 33%
• Protein Expression 33%
• Binding Affinity 33%
• Western Blot 16%
• Amino Terminal Sequence 16%
• Transcription Factor AP 1 16%
• ELISA 16%
• Reverse Transcription Polymerase Chain Reaction 16%
• Knee 16%
• Cartilage 16%
• Hip 16%
• Enzyme Activity 16%
• Gel Mobility Shift Assay 16%
• Immunopathogenesis 16%
• Signal Transduction 16%
• Transcription Factors 16%