TY - JOUR
T1 - Quantitative breast lesion classification based on multichannel distributions in shear-wave imaging
AU - Lo, Chung Ming
AU - Lai, Yi Chen
AU - Chou, Yi Hong
AU - Chang, Ruey Feng
N1 - Publisher Copyright:
© 2015 Elsevier Ireland Ltd.
PY - 2015/12
Y1 - 2015/12
N2 - Background and objectives: A computer-aided diagnosis (CAD) system based on the quantified color distributions in shear-wave elastography (SWE) was developed to evaluate the malignancies of breast tumors. Methods: For 57 benign and 31 malignant tumors, 18 SWE features were extracted from regions of interest (ROI), including the tumor and peritumoral areas. In the ROI, a histogram in each color channel was described using moments such as the mean, variance, skewness, and kurtosis. Moreover, three color channels were combined as a vector to evaluate tissue elasticity. The SWE features were then combined in a logistic regression classifier for breast tumor classification. Results: The performance of the CAD system achieved an accuracy of 81%. Combining the CAD system with a BI-RADS assessment obtained an Az improvement from 0.77 to 0.89 (p-value
AB - Background and objectives: A computer-aided diagnosis (CAD) system based on the quantified color distributions in shear-wave elastography (SWE) was developed to evaluate the malignancies of breast tumors. Methods: For 57 benign and 31 malignant tumors, 18 SWE features were extracted from regions of interest (ROI), including the tumor and peritumoral areas. In the ROI, a histogram in each color channel was described using moments such as the mean, variance, skewness, and kurtosis. Moreover, three color channels were combined as a vector to evaluate tissue elasticity. The SWE features were then combined in a logistic regression classifier for breast tumor classification. Results: The performance of the CAD system achieved an accuracy of 81%. Combining the CAD system with a BI-RADS assessment obtained an Az improvement from 0.77 to 0.89 (p-value
KW - Breast cancer
KW - Computer-aided diagnosis
KW - Histogram moment
KW - Shear-wave elastography
KW - Vector quantification
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U2 - 10.1016/j.cmpb.2015.09.004
DO - 10.1016/j.cmpb.2015.09.004
M3 - Article
C2 - 26421696
AN - SCOPUS:84947611836
SN - 0169-2607
VL - 122
SP - 354
EP - 361
JO - Computer Methods and Programs in Biomedicine
JF - Computer Methods and Programs in Biomedicine
IS - 3
ER -
