摘要
Purpose:: To assess sympathetic vasomotor activity and its changes with age, using pulsed wave Doppler ultrasound. Methods:: We recruited 20 young adults (24-37 years old) and 20 older individuals (60-81 years old). Pulsed wave Doppler ultrasound was applied over the right radial artery to measure blood flow at rest and after a voluntary inspiratory cough eliciting sympathetic activation. The maximal (Vmax), minimal (Vmin), time-averaged (TAMaxV) blood flow velocity, and the pulsatility index (PI) were calculated and compared between groups. Results:: At rest, PI was similar in both groups but Vmax and TAMaxV were higher in the older group (p < 0.05). Vmax, Vmin, and TAMaxV decreased, and PI increased after inspiratory cough in both groups (p ≤ 0.001), but this increase was lower in the older group (p < 0.001). TAMaxV after coughing was higher in the older group (p < 0.05). Heart rate did not differ significantly within or between groups. Conclusions:: The older group exhibited reduced vasomotor reactivity of the radial artery after sympathetic stimulus. Peripheral vasomotor response should be interpreted with caution in elderly populations.
原文 | 英語 |
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頁(從 - 到) | 383-389 |
頁數 | 7 |
期刊 | Journal of Clinical Ultrasound |
卷 | 39 |
發行號 | 7 |
DOIs | |
出版狀態 | 已發佈 - 9月 2011 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 放射學、核子醫學和影像學