TY - JOUR
T1 - Pulse Oximetry Monitor Feasible for Early Screening of Obstructive Sleep Apnea (OSA)
AU - Lin, Huei Chen
AU - Su, Chien Ling
AU - Ong, Jun Hui
AU - Tsai, kun ling
AU - Chen, Yu Wen
AU - Lin, Cheng Yu
AU - Chiang, Ling Ling
AU - Hung, Ching Hsia
N1 - Publisher Copyright:
© 2019, Taiwanese Society of Biomedical Engineering.
PY - 2020/2/1
Y1 - 2020/2/1
N2 - Purpose: We postulate that using a simple pulse oximetry monitor (POM) to detect the severity of OSA will help clinical staff confirm the need for early treatment. Hence, we compared the POM-derived oxygen desaturation index (ODI) (events/h) with the polysomnography (PSG)-derived apnea–hypopnea index (AHI) (events/h). Our study is intended to validate the SpO2 measurements and related ODI4% and ODI3% (events/h) calculations from POM associated with AHI and ODI from PSG based on 2007 and 2012 criteria. Methods: All 73 participants (mean age: 51.04 ± 13.14 years old) underwent an overnight PSG test and wore wristwatch POMs (PULSOX 300i) to automatically collect POM oxygen saturation (SpO2) data. Pearson correlation and the Bland and Altman method were used to verify the correlation between POM and PSG. Results: We found that the POM SpO2 and the PSG2007 and PSG2012 scores were significantly highly correlated (total record time [TRT] and lowest SpO2, R2 = 0.815 and 0.817; ODI4%, R2 = 0.912 and 0.863 and ODI3%, R2 = 0.930 and 0.914). AHI was significantly correlated with ODI4% and ODI3%, but ODI3% was nonsignificantly higher (ODI4%, r = 0.955–0.929; ODI3%, r = 0.965–0.956). Both the ODI3% and the ODI4% were highly diagnostically sensitive and specific. The ODI3% score with the AHI 15 events/h cutoff was nonsignificantly higher (area under the curve [AUC] = 0.99, AHI 15 events/h; AUC = 0.95, AHI 5 events/h). Conclusion: We conclude that the ODI3% score is a feasible early screening alternative for patients with moderate-to-severe OSA.
AB - Purpose: We postulate that using a simple pulse oximetry monitor (POM) to detect the severity of OSA will help clinical staff confirm the need for early treatment. Hence, we compared the POM-derived oxygen desaturation index (ODI) (events/h) with the polysomnography (PSG)-derived apnea–hypopnea index (AHI) (events/h). Our study is intended to validate the SpO2 measurements and related ODI4% and ODI3% (events/h) calculations from POM associated with AHI and ODI from PSG based on 2007 and 2012 criteria. Methods: All 73 participants (mean age: 51.04 ± 13.14 years old) underwent an overnight PSG test and wore wristwatch POMs (PULSOX 300i) to automatically collect POM oxygen saturation (SpO2) data. Pearson correlation and the Bland and Altman method were used to verify the correlation between POM and PSG. Results: We found that the POM SpO2 and the PSG2007 and PSG2012 scores were significantly highly correlated (total record time [TRT] and lowest SpO2, R2 = 0.815 and 0.817; ODI4%, R2 = 0.912 and 0.863 and ODI3%, R2 = 0.930 and 0.914). AHI was significantly correlated with ODI4% and ODI3%, but ODI3% was nonsignificantly higher (ODI4%, r = 0.955–0.929; ODI3%, r = 0.965–0.956). Both the ODI3% and the ODI4% were highly diagnostically sensitive and specific. The ODI3% score with the AHI 15 events/h cutoff was nonsignificantly higher (area under the curve [AUC] = 0.99, AHI 15 events/h; AUC = 0.95, AHI 5 events/h). Conclusion: We conclude that the ODI3% score is a feasible early screening alternative for patients with moderate-to-severe OSA.
KW - American Academy of Sleep Medicine
KW - Obstructive sleep apnea
KW - Oxygen desaturation index drops by 3% (events/h)
KW - Oxygen desaturation index drops by 4% (events/h)
KW - Polysomnography
KW - Pulse oximetry monitor
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U2 - 10.1007/s40846-019-00479-6
DO - 10.1007/s40846-019-00479-6
M3 - Article
AN - SCOPUS:85068795024
SN - 1609-0985
VL - 40
SP - 62
EP - 70
JO - Journal of Medical and Biological Engineering
JF - Journal of Medical and Biological Engineering
IS - 1
ER -