@article{498372d3796e495992b9642835490898,
title = "Prospective Therapeutic Applications of Platelet Extracellular Vesicles",
abstract = "There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for regenerative medicine and drug delivery. Blood-borne platelets represent a source of therapeutic EVs that is so far largely unexplored. Advantages of platelets as a cellular source of EVs include their established clinical value, regulated collection procedures, availability in a concentrated form, propensity to generate EVs, and unique composition and tissue-targeting capacity. This review analyzes the unique potential of platelet-derived (p-) EVs as therapeutic modalities and presents their inherent translational advantages for hemostasis, for regenerative medicine, and as drug-delivery vehicles.",
keywords = "drug delivery, exosome, extracellular vesicle, platelet, regeneration",
author = "Jancy Johnson and Wu, {Yu Wen} and Chantelle Blyth and Gregor Lichtfuss and Hadi Goubran and Thierry Burnouf",
note = "Funding Information: This study was supported by a grant ( 109–2314-B-038-126 ) from the Ministry of Science and Technology (MOST) of Taiwan and one ( NHRI-EX109-10920EI ) from the National Health Research Institute (NHRI) of Taiwan to T.B., Taipei Medical University (Taipei, Taiwan). Figures were created with objects sourced from Servier Medical Art ( http://smart.servier.com/ ), licensed under a Creative Commons Attribution 3.0 Generic License. Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2021",
month = jun,
doi = "10.1016/j.tibtech.2020.10.004",
language = "English",
volume = "39",
pages = "598--612",
journal = "Trends in Biotechnology",
issn = "0167-7799",
publisher = "Elsevier Limited",
number = "6",
}