Preparation of 6-phenyl- and 8-phenyl tetrahydroisoquinolines from boldine

Wei Jan Huang; Chung Hsiung Chen; Shoei Sheng Lee

doi:10.3987/com-03-9764

Preparation of 6-phenyl- and 8-phenyl tetrahydroisoquinolines from boldine

Wei Jan Huang, Chung Hsiung Chen, Shoei Sheng Lee

研究成果: 雜誌貢獻 › 文章 › 同行評審

7 引文斯高帕斯（Scopus）

摘要

Four 6-phenyl- and 8-phenyltetrahydroisoquinolines were prepared by structural modifications of boldine nucleus. These involved four major reaction steps, including solvolysis of 2-hydroxyaporphine, ozonolysis of the C-9, 10 double bond of phenanthrene nucleus leading to the key intermediate, and final Pictet-Spengler cyclization to respective target products.

原文	英語
頁（從 - 到）	1573-1588
頁數	16
期刊	Heterocycles
卷	60
發行號	7
DOIs	https://doi.org/10.3987/com-03-9764
出版狀態	已發佈 - 7月 1 2003
對外發佈	是

ASJC Scopus subject areas

分析化學
藥理
有機化學

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10.3987/com-03-9764

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abstract = "Four 6-phenyl- and 8-phenyltetrahydroisoquinolines were prepared by structural modifications of boldine nucleus. These involved four major reaction steps, including solvolysis of 2-hydroxyaporphine, ozonolysis of the C-9, 10 double bond of phenanthrene nucleus leading to the key intermediate, and final Pictet-Spengler cyclization to respective target products.",

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Preparation of 6-phenyl- and 8-phenyl tetrahydroisoquinolines from boldine

摘要

ASJC Scopus subject areas

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