Single crystals of the Fab fragment of a murine A/J anti-azophenylarsonate monoclonal antibody have been prepared by the vapor diffusion method. Antibody 3A7 uses the same combination of variable region gene segments (VK, JK, VH, JH) as do antizophenylarsonate antibodies bearing a predominant cross-reactive idiotype, but utilizes a different D gene segment. The crystals grow in the presence of β-octylglucoside as tetragonal bipyramids in the space group of either P41212 or P43312 and with unit cell dimensions of a = b = 77·9 A ̊, and c = 146·7 A ̊. They diffract X-rays to better than 2·7 Å resolution. Data up to 2·7 Å resolution have been collected.
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