Plant-Derived Natural Compounds as an Emerging Antiviral in Combating COVID-19

Mansi Singh, Shih Hsiu Lo, Rajni Dubey, Sudhashekhar Kumar, Kundan Kumar Chaubey, Sanjay Kumar

研究成果: 雜誌貢獻回顧型文獻同行評審

6 引文 斯高帕斯(Scopus)

摘要

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a human virus that burst at Wuhan in China and spread quickly over the world, leading to millions of deaths globally. The journey of this deadly virus to different mutant strains is still ongoing. The plethora of drugs and vaccines have been tested to cope up this pandemic. The herbal plants and different spices have received great attention during pandemic, because of their anti-inflammatory, and immunomodulatory properties in treating viruses and their symptoms. Also, it has been shown that nano-formulation of phytochemicals has potential therapeutic effect against COVID-19. Furthermore, the plant derived compound nano-formulation specifically increases its antiviral property by enhancing its bioavailability, solubility, and target-specific delivery system. This review highlights the potentiality of herbal plants and their phytochemical against SARS-CoV-2 utilizing different mechanisms such as blocking the ACE-2 receptors, inhibiting the main proteases, binding spike proteins and reducing the cytokine storms.
原文英語
頁(從 - 到)429-446
頁數18
期刊Indian Journal of Microbiology
63
發行號4
DOIs
出版狀態已發佈 - 12月 2023

ASJC Scopus subject areas

  • 微生物學

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