Photoreactivity of 5-iodouracil-containing DNA-Sso7d complex.

T. Oyoshi; H. Sugiyama; A. H. Wang

doi:10.1093/nass/42.1.171

Photoreactivity of 5-iodouracil-containing DNA-Sso7d complex.

T. Oyoshi, H. Sugiyama, A. H. Wang

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

摘要

X-ray structure of DNA-Sso7d complex indicated that binding of this protein causes sharp DNA bending. In order to examine whether this protein also causes DNA bending in solution, photoreactions of 1U-substituted DNA in the presence and the absence of Sso7d protein were investigated. It was found that the unusual intrastrand hydrogen abstraction at methyl of adjacent thymine occurred efficiently at the observed bending site of crystal structure.

原文	英語
頁（從 - 到）	171-172
頁數	2
期刊	Nucleic acids symposium series
發行號	42
DOIs	https://doi.org/10.1093/nass/42.1.171
出版狀態	已發佈 - 1999
對外發佈	是

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10.1093/nass/42.1.171

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abstract = "X-ray structure of DNA-Sso7d complex indicated that binding of this protein causes sharp DNA bending. In order to examine whether this protein also causes DNA bending in solution, photoreactions of 1U-substituted DNA in the presence and the absence of Sso7d protein were investigated. It was found that the unusual intrastrand hydrogen abstraction at methyl of adjacent thymine occurred efficiently at the observed bending site of crystal structure.",

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AB - X-ray structure of DNA-Sso7d complex indicated that binding of this protein causes sharp DNA bending. In order to examine whether this protein also causes DNA bending in solution, photoreactions of 1U-substituted DNA in the presence and the absence of Sso7d protein were investigated. It was found that the unusual intrastrand hydrogen abstraction at methyl of adjacent thymine occurred efficiently at the observed bending site of crystal structure.

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Photoreactivity of 5-iodouracil-containing DNA-Sso7d complex.

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