Photoproducts of naproxen in alcoholic solvents

Hsin Tsung Ho; An-Bang Wu; Pen Yuan Lin; Jen Ai Lee; Pen Yueh Hung

Photoproducts of naproxen in alcoholic solvents

Hsin Tsung Ho
, An-Bang Wu
, Pen Yuan Lin
, Jen Ai Lee
, Pen Yueh Hung

研究成果: 書貢獻/報告類型 › 章節

摘要

A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.

原文	英語
主出版物標題	Biomedical Chromatography
發行者	Nova Science Publishers, Inc.
頁面	159-170
頁數	12
ISBN（電子）	9781616684709
ISBN（列印）	9781607412915
出版狀態	已發佈 - 1月 1 2010

ASJC Scopus subject areas

一般農業與生物科學
一般生物化學，遺傳學和分子生物學

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引用此

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abstract = "A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.",

keywords = "EI-MS, HPLC, Naproxen, Photochemistry",

author = "Ho, \{Hsin Tsung\} and An-Bang Wu and Lin, \{Pen Yuan\} and Lee, \{Jen Ai\} and Hung, \{Pen Yueh\}",

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T1 - Photoproducts of naproxen in alcoholic solvents

AU - Ho, Hsin Tsung

AU - Wu, An-Bang

AU - Lin, Pen Yuan

AU - Lee, Jen Ai

AU - Hung, Pen Yueh

PY - 2010/1/1

Y1 - 2010/1/1

N2 - A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.

AB - A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.

KW - EI-MS

KW - HPLC

KW - Naproxen

KW - Photochemistry

UR - https://www.scopus.com/pages/publications/85016789591

UR - https://www.scopus.com/pages/publications/85016789591#tab=citedBy

M3 - Chapter

AN - SCOPUS:85016789591

SN - 9781607412915

SP - 159

EP - 170

BT - Biomedical Chromatography

PB - Nova Science Publishers, Inc.

ER -

Photoproducts of naproxen in alcoholic solvents

摘要

ASJC Scopus subject areas

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