Photoproducts of naproxen in alcoholic solvents

Hsin Tsung Ho; An Bang Wu; Pen Yuan Lin; Jen Ai Lee; Pen Yueh Hung

Photoproducts of naproxen in alcoholic solvents

Hsin Tsung Ho, An Bang Wu, Pen Yuan Lin, Jen Ai Lee, Pen Yueh Hung

研究成果: 書貢獻/報告類型 › 章節

摘要

A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.

原文	英語
主出版物標題	Biomedical Chromatography
發行者	Nova Science Publishers, Inc.
頁面	159-170
頁數	12
ISBN（電子）	9781616684709
ISBN（列印）	9781607412915
出版狀態	已發佈 - 1月 1 2010

ASJC Scopus subject areas

農業與生物科學 (全部)
生物化學、遺傳與分子生物學 (全部)

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abstract = "A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.",

keywords = "EI-MS, HPLC, Naproxen, Photochemistry",

author = "Ho, {Hsin Tsung} and Wu, {An Bang} and Lin, {Pen Yuan} and Lee, {Jen Ai} and Hung, {Pen Yueh}",

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AU - Ho, Hsin Tsung

AU - Wu, An Bang

AU - Lin, Pen Yuan

AU - Lee, Jen Ai

AU - Hung, Pen Yueh

PY - 2010/1/1

Y1 - 2010/1/1

N2 - A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.

AB - A sample of 5 mM naproxen in methanol or ethanol was photoirradiated with a Hanovia 200 W high-pressure quartz Hg lamp. In total, 6 photoproducts derived from each sample were observed from the HPLC chromatograms. Four major photoproducts were separated, and their structures elucidated by EI-MS and various spectroscopic methods. A reaction scheme of naproxen in alcoholic solvents is proposed: the photochemical reaction routes occur mainly via decarboxylation and esterification, followed by oxidation with singlet oxygen to produce an alcohol and a ketone.

KW - EI-MS

KW - HPLC

KW - Naproxen

KW - Photochemistry

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M3 - Chapter

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SN - 9781607412915

SP - 159

EP - 170

BT - Biomedical Chromatography

PB - Nova Science Publishers, Inc.

ER -

Photoproducts of naproxen in alcoholic solvents

摘要

ASJC Scopus subject areas

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