摘要
Controversy remains regarding the risk of bone abnormalities due to enzyme-inducing antiepileptic drugs (EIAEDs) and non-enzyme-inducing antiepileptic drugs (NEIAEDs). This case-control study aimed to investigate the possible association between osteoporosis and epilepsy disease and AEDs therapy using a population-based dataset in Taiwan. We first identified 48,102 cases, =18 years of age, who received a first-time diagnosis of osteoporosis, and then randomly selected 144,306 controls. We used conditional logistic regression analyses to compute the odds ratio (OR) and corresponding 95% confidence interval (CI) to compare a previous diagnosis of epilepsy between cases and controls. We found that of the 192,408 sampled subjects, epilepsy was found in 117 (0.24%) cases and 240 (0.17%) controls (p
原文 | 英語 |
---|---|
頁(從 - 到) | 333-342 |
頁數 | 10 |
期刊 | Epileptic Disorders |
卷 | 16 |
發行號 | 3 |
DOIs | |
出版狀態 | 已發佈 - 9月 1 2014 |
ASJC Scopus subject areas
- 神經內科
- 神經病學(臨床)