Novel biomarker analysis of pleural effusion enhances differentiation of tuberculous from malignant pleural effusion

Kuan Yuan Chen; Po Hao Feng; Chih Cheng Chang; Tzu Tao Chen; Hsiao Chi Chuang; Chun Nin Lee; Chien Ling Su; Lian Yu Lin; Kang Yun Lee

doi:10.2147/IJGM.S100237

Novel biomarker analysis of pleural effusion enhances differentiation of tuberculous from malignant pleural effusion

Kuan Yuan Chen, Po Hao Feng, Chih Cheng Chang, Tzu Tao Chen, Hsiao Chi Chuang, Chun Nin Lee, Chien Ling Su, Lian Yu Lin, Kang Yun Lee

研究成果: 雜誌貢獻 › 文章 › 同行評審

23 引文斯高帕斯（Scopus）

摘要

Lymphocytic pleurisy is commonly observed in tuberculosis and cancer. Noninvasive biomarkers are needed to distinguish tuberculous pleural effusion (TPE) from malignant pleural effusion (MPE) because current clinical diagnostic procedures are often invasive. We identified immune response biomarkers that can discriminate between TPE and MPE. Fourteen pleural effusion biomarkers were compared in 22 MPE patients and five TPE patients. Of the innate immunity biomarkers, the median levels of interleukin (IL)-1βand interferon-induced protein-10 (IP-10) were higher in TPE patients than in MPE patients (P

原文	英語
頁（從 - 到）	183-189
頁數	7
期刊	International Journal of General Medicine
卷	9
DOIs	https://doi.org/10.2147/IJGM.S100237
出版狀態	已發佈 - 6月 11 2016

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一般醫學

UN SDG

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10.2147/IJGM.S100237

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引用此

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abstract = "Lymphocytic pleurisy is commonly observed in tuberculosis and cancer. Noninvasive biomarkers are needed to distinguish tuberculous pleural effusion (TPE) from malignant pleural effusion (MPE) because current clinical diagnostic procedures are often invasive. We identified immune response biomarkers that can discriminate between TPE and MPE. Fourteen pleural effusion biomarkers were compared in 22 MPE patients and five TPE patients. Of the innate immunity biomarkers, the median levels of interleukin (IL)-1βand interferon-induced protein-10 (IP-10) were higher in TPE patients than in MPE patients (P",

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AU - Chen, Kuan Yuan

AU - Feng, Po Hao

AU - Chang, Chih Cheng

AU - Chen, Tzu Tao

AU - Chuang, Hsiao Chi

AU - Lee, Chun Nin

AU - Su, Chien Ling

AU - Lin, Lian Yu

AU - Lee, Kang Yun

PY - 2016/6/11

Y1 - 2016/6/11

N2 - Lymphocytic pleurisy is commonly observed in tuberculosis and cancer. Noninvasive biomarkers are needed to distinguish tuberculous pleural effusion (TPE) from malignant pleural effusion (MPE) because current clinical diagnostic procedures are often invasive. We identified immune response biomarkers that can discriminate between TPE and MPE. Fourteen pleural effusion biomarkers were compared in 22 MPE patients and five TPE patients. Of the innate immunity biomarkers, the median levels of interleukin (IL)-1βand interferon-induced protein-10 (IP-10) were higher in TPE patients than in MPE patients (P

AB - Lymphocytic pleurisy is commonly observed in tuberculosis and cancer. Noninvasive biomarkers are needed to distinguish tuberculous pleural effusion (TPE) from malignant pleural effusion (MPE) because current clinical diagnostic procedures are often invasive. We identified immune response biomarkers that can discriminate between TPE and MPE. Fourteen pleural effusion biomarkers were compared in 22 MPE patients and five TPE patients. Of the innate immunity biomarkers, the median levels of interleukin (IL)-1βand interferon-induced protein-10 (IP-10) were higher in TPE patients than in MPE patients (P

KW - Biomarkers

KW - Lung cancer

KW - Malignant pleural effusion

KW - Tuberculous pleural effusion

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Novel biomarker analysis of pleural effusion enhances differentiation of tuberculous from malignant pleural effusion

摘要

ASJC Scopus subject areas

UN SDG

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