Newly diagnosed major depressive disorder and the risk of erectile dysfunction: A population-based cohort study in Taiwan

Shiau Shian Huang, Ching Heng Lin, Chin Hong Chan, El Wui Loh, Tsuo Hung Lan

研究成果: 雜誌貢獻文章同行評審

16 引文 斯高帕斯(Scopus)

摘要

Introduction: The primary aim of this study was to explore the incidence rate of erectile dysfunction (ED) among major depressive disorder (MDD) patients in an Asian country. The second aim was to compare the risk of ED in MDD patients that were treated using antidepressants with a high risk-ED, antidepressants with a low risk-ED, or without treatment. Methods: We identified 4339 male patients with newly diagnosed MDD using the National Health Database. Four matched controls per case were selected for the study. Results: The mean age of the participants was 42.3±16.9. A higher crude HR of 3.6 (95% CI: 2.8-4.6) was seen in the male patients with MDD. After adjusting for obesity, monthly income, urbanization level, and comorbidity, the MDD patients had a 3.2-fold higher HR for an ED diagnosis than the controls. Patients with untreated depression had the highest risk of ED, compared to the control group (HR=3.9). Patients treated with IHiRA had a medium risk of developing ED (HR=3.6), and patients treated with ILoRA had the lowest risk of ED (HR: 2.5). Conclusion: This prospective cohort study found an association between ED and prior MDD. Patients with untreated depression may have the highest risk of developing ED.
原文英語
頁(從 - 到)601-606
頁數6
期刊Psychiatry Research
210
發行號2
DOIs
出版狀態已發佈 - 12月 15 2013
對外發佈

ASJC Scopus subject areas

  • 精神病學和心理健康
  • 生物精神病學

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