摘要
Three new briaran diterpenes, 2β-acetoxy-2-(debutyryloxy)stecholide E (3), 9-deacetylstylatulide lactone (4), and 4β-acetoxy-9-deacetylstylatulide lactone (5), and two known diterpenes, brianthein W (1) and 9- deacetylbriareolide H (2), have been isolated from a Briareum sp. of gorgonian. The structures and relative stereochemistry of these compounds were determined by spectroscopic and chemical methods. Diterpenes 2-4 and the corresponding 9-acetyl derivatives 6, 7, and 12 exhibited cytotoxicity toward various cancer cell lines.
原文 | 英語 |
---|---|
頁(從 - 到) | 935-938 |
頁數 | 4 |
期刊 | Journal of Natural Products |
卷 | 59 |
發行號 | 10 |
DOIs | |
出版狀態 | 已發佈 - 10月 1 1996 |
ASJC Scopus subject areas
- 分析化學
- 分子醫學
- 藥理
- 藥學科學
- 藥物發現
- 補充和替代醫學
- 有機化學