Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis

Yi Ying Wu, Chia Ching Hsieh, Chia Ying Li, Wen Huei Chang, Jih Jung Chen, Kuei Hung Lai, Zhi Hong Wen, Hsu Ming Chung

研究成果: 雜誌貢獻文章同行評審

2 引文 斯高帕斯(Scopus)


Chemical examination of Sinularia querciformis afforded one new cembranoid, querciformolide F (1), along with four known cembranoids, sinulariolone (2), granosolide A (3), querciformolide A (4), and sinulariolide (5). The structures of these compounds were determined by extensive spectroscopic (IR, ESIMS, 1H NMR, and 13C NMR) analysis and by comparison with those previously reported in the literature. Compounds 2 to 4 were found to exhibit significant anti-inflammatory activity in lipopolysaccharide (LPS)-induced RAW264.7 mouse macrophages through attenuating the expression of the inducible nitric oxide synthase (iNOS) proteins.
期刊Natural Product Communications
出版狀態已發佈 - 11月 2021

ASJC Scopus subject areas

  • 藥理
  • 藥物發現
  • 植物科學
  • 補充和替代醫學


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