Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis

Yi Ying Wu; Chia Ching Hsieh; Chia Ying Li; Wen Huei Chang; Jih Jung Chen; Kuei Hung Lai; Zhi Hong Wen; Hsu Ming Chung

doi:10.1177/1934578X211059299

Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis

Yi Ying Wu, Chia Ching Hsieh, Chia Ying Li, Wen Huei Chang, Jih Jung Chen, Kuei Hung Lai, Zhi Hong Wen, Hsu Ming Chung

研究成果: 雜誌貢獻 › 文章 › 同行評審

2 引文斯高帕斯（Scopus）

摘要

Chemical examination of Sinularia querciformis afforded one new cembranoid, querciformolide F (1), along with four known cembranoids, sinulariolone (2), granosolide A (3), querciformolide A (4), and sinulariolide (5). The structures of these compounds were determined by extensive spectroscopic (IR, ESIMS, 1H NMR, and 13C NMR) analysis and by comparison with those previously reported in the literature. Compounds 2 to 4 were found to exhibit significant anti-inflammatory activity in lipopolysaccharide (LPS)-induced RAW264.7 mouse macrophages through attenuating the expression of the inducible nitric oxide synthase (iNOS) proteins.

原文	英語
期刊	Natural Product Communications
卷	16
發行號	11
DOIs	https://doi.org/10.1177/1934578X211059299
出版狀態	已發佈 - 11月 2021

ASJC Scopus subject areas

藥理
藥物發現
植物科學
補充和替代醫學

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10.1177/1934578X211059299

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Link to publication in Scopus

sj-docx-1-npx-10.1177_1934578X211059299 - Supplemental material for Natural Cembrane Diterpenoids From the Soft Coral <i>Sinularia querciformis</i>
Wen, Z.-H. (Creator), Hsieh, C.-C. (Creator), Li, C.-Y. (Creator), Chung, H.-M. (Creator), Chang, W.-H. (Creator), Lai, K.-H. (Creator), Chen, J.-J. (Creator) & Wu, Y.-Y. (Creator), SAGE Journals, 2021
DOI: 10.25384/sage.17112792.v1, https://sage.figshare.com/articles/journal_contribution/sj-docx-1-npx-10_1177_1934578X211059299_-_Supplemental_material_for_Natural_Cembrane_Diterpenoids_From_the_Soft_Coral_i_Sinularia_querciformis_i_/17112792/1
資料集: Dataset
Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis
Wu, Y.-Y. (Creator), Hsieh, C.-C. (Creator), Li, C.-Y. (Creator), Chang, W.-H. (Creator), Chen, J.-J. (Creator), Lai, K.-H. (Creator), Wen, Z.-H. (Creator) & Chung, H.-M. (Creator), SAGE Journals, 2021
DOI: 10.25384/sage.c.5733780.v1, https://sage.figshare.com/collections/Natural_Cembrane_Diterpenoids_From_the_Soft_Coral_i_Sinularia_querciformis_i_/5733780/1
資料集: Dataset

引用此

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title = "Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis",

abstract = "Chemical examination of Sinularia querciformis afforded one new cembranoid, querciformolide F (1), along with four known cembranoids, sinulariolone (2), granosolide A (3), querciformolide A (4), and sinulariolide (5). The structures of these compounds were determined by extensive spectroscopic (IR, ESIMS, 1H NMR, and 13C NMR) analysis and by comparison with those previously reported in the literature. Compounds 2 to 4 were found to exhibit significant anti-inflammatory activity in lipopolysaccharide (LPS)-induced RAW264.7 mouse macrophages through attenuating the expression of the inducible nitric oxide synthase (iNOS) proteins.",

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author = "Wu, {Yi Ying} and Hsieh, {Chia Ching} and Li, {Chia Ying} and Chang, {Wen Huei} and Chen, {Jih Jung} and Lai, {Kuei Hung} and Wen, {Zhi Hong} and Chung, {Hsu Ming}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Ministry of Science and Technology, Taiwan (grant number MOST 110-2320-B-153 -001). Publisher Copyright: {\textcopyright} The Author(s) 2021.",

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AU - Wen, Zhi Hong

AU - Chung, Hsu Ming

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Ministry of Science and Technology, Taiwan (grant number MOST 110-2320-B-153 -001). Publisher Copyright: © The Author(s) 2021.

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AB - Chemical examination of Sinularia querciformis afforded one new cembranoid, querciformolide F (1), along with four known cembranoids, sinulariolone (2), granosolide A (3), querciformolide A (4), and sinulariolide (5). The structures of these compounds were determined by extensive spectroscopic (IR, ESIMS, 1H NMR, and 13C NMR) analysis and by comparison with those previously reported in the literature. Compounds 2 to 4 were found to exhibit significant anti-inflammatory activity in lipopolysaccharide (LPS)-induced RAW264.7 mouse macrophages through attenuating the expression of the inducible nitric oxide synthase (iNOS) proteins.

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Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis

摘要

ASJC Scopus subject areas

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資料集

sj-docx-1-npx-10.1177_1934578X211059299 - Supplemental material for Natural Cembrane Diterpenoids From the Soft Coral <i>Sinularia querciformis</i>

Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis

引用此