TY - JOUR
T1 - Multicentric reticulohistiocytosis in a Taiwanese woman with Sjögren syndrome
AU - Cheng, Lan Hsin
AU - Chiang, Ying Yi
N1 - Publisher Copyright:
© 2015, Taiwanese Dermatological Association. Published by Elsevier Taiwan LLC.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Multicentric reticulohistiocytosis is a rare, non-Langerhans cell histiocytosis characterized by specific skin lesions and destructive arthritis. Clinically, it generally presents with multiple reddish-brown papulonodules over the hands, face, and trunk. The associated destructive arthropathy tends to be severe, with 50% of patients developing arthritis mutilans. Approximately 25-30% of patients present with neoplasia. Coexisting autoimmune diseases are also commonly reported. Here we report the case of a 59-year-old Taiwanese woman with underlying Sjögren syndrome who presented with the typical skin manifestations of multicentric reticulohistiocytosis and early interphalangeal joint involvement. The patient later showed partial response to methotrexate treatment.
AB - Multicentric reticulohistiocytosis is a rare, non-Langerhans cell histiocytosis characterized by specific skin lesions and destructive arthritis. Clinically, it generally presents with multiple reddish-brown papulonodules over the hands, face, and trunk. The associated destructive arthropathy tends to be severe, with 50% of patients developing arthritis mutilans. Approximately 25-30% of patients present with neoplasia. Coexisting autoimmune diseases are also commonly reported. Here we report the case of a 59-year-old Taiwanese woman with underlying Sjögren syndrome who presented with the typical skin manifestations of multicentric reticulohistiocytosis and early interphalangeal joint involvement. The patient later showed partial response to methotrexate treatment.
KW - Multicentric reticulohistiocytosis
KW - Sjögren syndrome
KW - dermatomyositis
KW - erosive polyarthropathy
KW - non-langerhans cell histiocytosis
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U2 - 10.1016/j.dsi.2015.08.001
DO - 10.1016/j.dsi.2015.08.001
M3 - Article
AN - SCOPUS:84948807281
SN - 1027-8117
VL - 34
SP - 42
EP - 45
JO - Dermatologica Sinica
JF - Dermatologica Sinica
IS - 1
ER -