A majority of naturally occurring cancers associated with retrovirus infection are caused by non-acute retroviruses. These viruses do not carry oncogenes of their own and induce cancer in their hosts only after a long latency period. They are believed to be the progenitor viruses which gave rise to the acute retroviruses through recombination with host oncogenes (1,2). The hosts of these viruses include most vertebrate species. An excellent review of the neoplasms induced by non-acute retroviruses of a variety of organisms is presented by Varmus (3). The focus of this review will be restricted to the non-acute avian retroviruses.
|Springer, Boston, MA
|已發佈 - 1987