摘要
MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.
原文 | 英語 |
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頁(從 - 到) | 1144-1148 |
頁數 | 5 |
期刊 | British Journal of Cancer |
卷 | 103 |
發行號 | 8 |
DOIs | |
出版狀態 | 已發佈 - 10月 12 2010 |
ASJC Scopus subject areas
- 腫瘤科
- 癌症研究