Metabolic syndrome and the risk of suicide: A community-based integrated screening samples cohort study

Jung Chen Chang, Amy Ming Fang Yen, Chau Shoun Lee, Sam Li Sheng Chen, Sherry Yueh Hsia Chiu, Jean Ching Yuan Fann, Hsiu Hsi Chen

研究成果: 雜誌貢獻文章同行評審

18 引文 斯高帕斯(Scopus)


OBJECTIVE: Metabolic syndrome (MetS) is reportedly associated with mental disorders that are known to increase the risk of suicide. However, it is not known whether this association is independent of other risk indicators of suicide. This study therefore investigated whether metabolic abnormalities increase the risk of suicide during a 10-year follow-up period. METHODS: This prospective study enrolled participants from a community-based integrated screening samples cohort in Taiwan. Of the 76,297 people recruited for this study, 12,094 had MetS at baseline. The independent variables were MetS and its components such as high blood pressure and high blood lipid levels. The outcome was death from suicide (n = 146). RESULTS: MetS was associated with an increased risk of suicide risk by 16% per MetS component (95% confidence interval [CI] = 1%-33%), adjusting for demographics, life-style factors, and clinical correlates. Of the five MetS components, elevated blood pressure was independently associated with suicide-related mortality (adjusted hazard ratio [aHR] = 1.49, 95% CI = 1.03-2.15). CONCLUSIONS: This analysis of community-based longitudinal data showed that MetS and its components, particularly elevated blood pressure, correlated positively with suicide risk after controlling other factors. Therefore, public mental health interventions targeting suicide reduction may need to specifically focus on individuals with hypertension and other components of the MetS.
頁(從 - 到)807-814
期刊Psychosomatic Medicine
出版狀態已發佈 - 11月 2013

ASJC Scopus subject areas

  • 精神病學和心理健康
  • 應用心理學
  • 藝術與人文(雜項)
  • 發展與教育心理學


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