Mesoporous europium-doped titania nanoparticles (Eu-MTNs) for luminescence-based intracellular bio-imaging

Kuan Chou Chen, Saikat Dutta, Yusuke Yamauchi, Saad M. Alshehri, Mai Thanh Nguyen, Tetsu Yonezawa, Kun Hung Shen, Kevin C.W. Wu

研究成果: 雜誌貢獻文章同行評審

6 引文 斯高帕斯(Scopus)

摘要

Monodisperse and mesoporous europium (Eu)-doped titania nanoparticles (denoted as Eu-MTNs) were prepared by a co-synthesis method with the presence of a cationic surfactant (i.e., CTAB). A maximum loading amount of 8 mol% of Eu could be successfully incorporated into the framework of MTNs. The synthesized Eu-MTNs samples were characterized with X-ray diffraction (XRD) and scanning electron microscopy (SEM), with their luminescent property examined by photoluminescence (PL). Under ultraviolet irradiation, the Eu-MTNs samples exhibit several characteristic luminescence corresponding to 5D0-7Fj for Eu+3 ions, which can be attributed to the energy transfer from titania nanocrystallite to Eu3+ ions dispersed in amorphous mesoporous titania region. The potential intracellular bio-imaging application of the synthesized Eu-MTN nanoparticles was demonstrated with a breast cancer cell line (i.e., BT-20). High biocompatibility and strong luminescence of the Eu-MTNs show great potential in biomedical applications.

原文英語
頁(從 - 到)9802-9806
頁數5
期刊Journal of Nanoscience and Nanotechnology
15
發行號12
DOIs
出版狀態已發佈 - 12月 1 2015

ASJC Scopus subject areas

  • 生物工程
  • 一般化學
  • 生物醫學工程
  • 一般材料科學
  • 凝聚態物理學

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