Mental fatigue mediates the relationship between cognitive functions and return to productive activity following traumatic brain injury: a mediation analysis

Pin Yuan Chen, Shu Hua Hsieh, Che Kuang Lin, Li Wei, Yu Kai Su, Pei Shan Tsai, Hsiao Yean Chiu

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

PURPOSE: We performed a mediation analysis to investigate how mental fatigue mediates the relationship between cognitive functions and the return to productive activity following TBI.

METHODS: One hundred and one people (≥20 years) with first-time TBI more than 3 months who completed a series of cognitive tasks followed by Chinese versions of the Mental Fatigue Scale and Community Integration Questionnaire-Revised. Mediation analysis was used to test our hypotheses.

RESULTS: Recognition memory and information processing speed were the only cognitive functions correlated with mental fatigue (B = -0.56 and -0.37, P = .04 and < 0.001) and the return to productive activity (B = 0.69 and 0.19, both P < .001) after controlling for confounders. Mental fatigue partially mediated the associations of recognition memory and information processing speed with the return to productive activity (B = 0.15 and 0.08, P = .001 and < 0.001, proportion of mediation = 22% and 46%) after the adjustment of confounders.

CONCLUSIONS: The findings suggest that mental fatigue can partially mediate the relationship between cognitive deficits and return to productive activity. Mental fatigue can be considered a crucial, treatable mediator of the adverse effects of cognitive impairment upon return to productive activity following TBI.

原文英語
頁(從 - 到)32-38
頁數7
期刊Brain Injury
36
發行號1
DOIs
出版狀態已發佈 - 1月 2 2022

ASJC Scopus subject areas

  • 神經病學(臨床)
  • 發展與教育心理學
  • 神經科學(雜項)

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