Maintenance of mitochondrial DNA copy number and expression are essential for preservation of mitochondrial function and cell growth

Medicine & Life Sciences

• Mitochondrial DNA 100%
• Maintenance 66%
• Clone Cells 56%
• Growth 48%
• Gene Expression 21%
• Small Interfering RNA 19%
• mitochondrial transcription factor A 18%
• Adenosine Triphosphate 18%
• Mitochondrial RNA 17%
• Cytochromes b 17%
• Gene Knockdown Techniques 15%
• 8-Hydroxy-2'-Deoxyguanosine 15%
• Organelle Biogenesis 15%
• Electron Transport Complex IV 13%
• Protein Subunits 13%
• Mitochondrial Proteins 13%
• Mutation 13%
• Enzymes 13%
• Point Mutation 11%
• Transfection 10%
• Down-Regulation 8%
• Proteins 4%

Chemical Compounds

• Mutation 80%
• Percent Reduction 74%
• Cytochrome 55%
• Small Interfering RNA 43%
• Silencing RNA 41%
• Protein 39%
• Enzyme Activity 26%
• Reduction 14%